Understanding Lyophilization Formulation Development
نویسنده
چکیده
www.pharmtech.com yophilization or freeze-drying is often used to stabilize various pharmaceutical products, including virus vaccines, protein and peptide formulations, liposome, and small-chemical drug formulations (1–4). Often a pharmaceutical product may be susceptible to physical and chemical degradation when stored as a ready-to-use solution. The goal of the formulations scientist is to identify the right formulation conditions, the right excipients in optimal quantities, and the right dosage form to maximize stability, biological activity, safety, and marketability of a particular product.
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